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Primary triple-negative breast cancers (TNBCs), a tumour type defined by lack of oestrogen receptor, progesterone receptor and ERBB2 gene amplification, represent approximately 16% of all breast cancers. Here we show in 104 TNBC cases that at the time of diagnosis these cancers exhibit a wide and continuous spectrum of genomic evolution, with some having(More)
Visually examining RNA structures can greatly aid in understanding their potential functional roles and in evaluating the performance of structure prediction algorithms. As many functional roles of RNA structures can already be studied given the secondary structure of the RNA, various methods have been devised for visualizing RNA secondary structures. Most(More)
This paper describes a Hong Kong MTR Corporation subway project to enhance and extend the current Web-based Engineering Works and Traffic Information Management System (ETMS) with an intelligent " AI Engine. " The challenge is to be able to fully and accurately encapsulate all the necessary domain and operation knowledge on subway engineering works and to(More)
one copy of any article(s) in SHURA to facilitate their private study or for non-commercial research. You may not engage in further distribution of the material or use it for any profit-making activities or any commercial gain. Abstract The outcome of football matches is heavily dependent on referee decisions regarding violations of the offside rule.(More)
e-RNA offers a free and open-access collection of five published RNA sequence analysis tools, each solving specific problems not readily addressed by other available tools. Given multiple sequence alignments, Transat detects all conserved helices, including those expected in a final structure, but also transient, alternative and pseudo-knotted helices.(More)
In Hong Kong, elderly patients discharged from hospital are at high risk of unplanned readmission. The Integrated Care Model (ICM) program is introduced to provide continuous and coordinated care for high risk elders from hospital to community to prevent unplanned readmission. A multidisciplinary working group was set up to address the requirements on(More)
This paper describes how the MTR Corporation of Hong Kong made use of Artificial Intelligence (AI) and Web 2.0 technology to computerize and streamline daily maintenance scheduling. The application is called the Engineering Works and Traffic Information Management System (ETMS), an intelligent workflow system for maintenance scheduling. ETMS oversees over a(More)