Peptidoglycans (PGNs) are immunogenic bacterial surface patterns that trigger immune activation in metazoans and plants. It is generally unknown how complex bacterial structures such as PGNs are perceived by plant pattern recognition receptors (PRRs) and whether host hydrolytic activities facilitate decomposition of bacterial matrices and generation of… (More)
Multiple mechanisms have been correlated with daptomycin-resistance (DAP-R) in Staphylococcus aureus. However, one common phenotype observed in many DAP-R S. Aureus strains is a thickened cell wall (CW). The first evidence for an impact of CW-linked glycopolymers on this phenotype was recently demonstrated in a single, well-characterized DAP-R… (More)
Bacterial conjugation normally involves the unidirectional transfer of DNA from donor to recipient. Occasionally, conjugation results in the transfer of DNA from recipient to donor, a phenomenon known as retrotransfer. Two distinct models have been generally considered for the mechanism of retrotransfer. In the two-way conduction model, no transfer of the… (More)
Peptidoglycan (PGN) is ubiquitous in nearly all bacterial species. The PGN sacculus protects the cells against their own internal turgor making PGN one of the most important targets for antibacterial treatment. Within the last sixty years PGN composition has been intensively studied by various methods. The breakthrough was the application of HPLC technology… (More)
Within the last 60 years peptidoglycan (PGN) composition of bacteria has been intensively studied by various methods. However, preparation of pure PGN relied on a very time-consuming method. We established a purification protocol which can be completely performed in plastic reaction tubes or even microtiter plates within 24 hours. The muropeptides can be… (More)
The Gram-positive bacterium Staphylococcus carnosus (S. carnosus) TM300 is an apathogenic staphylococcal species commonly used in meat starter cultures. As with all Gram-positive bacteria, its cytoplasmic membrane is surrounded by a thick peptidoglycan (PGN) or murein sacculus consisting of several layers of glycan strands cross-linked by peptides. In… (More)
Das Seminar " Mobile und verteilte Systeme – Ubiquitous Computing " am Telecooperation Office (TecO) erfreut sich großer Beliebtheit. Der vorliegende interne Bericht enthält die studentischen Beiträge zu diesem Seminar, das im WS 2006/07 in dieser Form zum fünften Mal stattgefunden hat.