Daniel J Morath

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Iron deficiency in children is associated with a number of neural defects including hypomyelination. It has been hypothesized by others that this hypomyelination is due to a failure in myelin production. Other possibilities include failure in the generation of oligodendrocytes from their precursor cells or an interruption in oligodendrocyte maturation.(More)
One of the hallmarks of the pathology of iron deficiency in children is neurological disabilities that are often associated with hypomyelination. It has been hypothesized that this amyelination is mainly due to a disruption of myelin generation during the early postnatal stages when oligodendrocytes mature to generate myelin producing cell. In addition to(More)
It is neither known why hormonal and nutritional deficiencies only cause neurological abnormalities at particular periods of development, nor is it known why repair only occurs if normal metabolic status is restored within a particular temporal window. We propose that these maladies are precursor cell diseases, in which the normal balance between(More)
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