Daniel J Fox

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We have previously reported rescue from noise-induced auditory brainstem response (ABR) threshold shifts with d-methionine (d-met) administration 1 h after noise exposure. The present study investigated further d-met rescue intervals at 3, 5 and 7 h post-noise exposure. Chinchillas laniger were exposed to a 6 h 105 dB sound pressure level (dB SPL) octave(More)
OBJECTIVE This study tested multiple dosing epochs of pre-loaded D-methionine (D-met) for otoprotection from noise-induced hearing loss (NIHL). DESIGN Auditory brainstem response (ABR) thresholds were measured at baseline, 1 day, and 21 days following a 6-hour 105 dB sound pressure level (SPL) octave band noise (OBN) exposure. Outer hair cell (OHC) counts(More)
It is shown that a (curved) projective structure on a smooth manifold determines on the Poisson algebra of smooth, fiberwise-polynomial functions on the cotangent bundle a oneparameter family of graded star products. For a particular value of the parameter (corresponding to half-densities) the star product is symmetric, and specializes in the projectively(More)
We present a case of a 21-year-old female with congenitally corrected transposition of the great vessels and episodes of supraventricular tachycardia. We performed an electrophysiological study and successful ablation using an electro-anatomical mapping system. A single His bundle appeared to be located at the apex of the triangle of Koch and at(More)
It is shown that coassociative cones in R7 that are r-oriented and ruled by 2-planes are equivalent to CR-holomorphic curves in the oriented Grassmanian of 2-planes in R7. The geometry of these CR-holomorphic curves is studied and related to holomorphic curves in S6. This leads to an equivalence between associative cones on one side and the coassociative(More)
BACKGROUND Tobramycin is a critical cystic fibrosis treatment however it causes ototoxicity. This study tested d-methionine protection from tobramycin-induced ototoxicity and potential antimicrobial interference. METHODS Auditory brainstem responses (ABRs) and outer hair cell (OHC) quantifications measured protection in guinea pigs treated with tobramycin(More)
Uhlenbeck proved that a set of simple elements generates the group of rational loops in GL(n,C) that satisfy the U(n)-reality condition. For an arbitrary complex reductive group, a choice of representation defines a notion of rationality and enables us to write down a natural set of simple elements. Using these simple elements we prove generator theorems(More)
A contact path geometry is a family of paths in a contact manifold each of which is everywhere tangent to the contact distribution and such that given a point and a one-dimensional subspace of the contact distribution at that point there is a unique path of the family passing through the given point and tangent to the given subspace. A contact projective(More)