Daniel I Flitcroft

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It has long been recognised that chromatic aberration can introduce luminance artifacts into nominally isoluminant colour stimuli. In this study the effects of chromatic aberration (along with those of defocus and stimulus spatial frequency) on the chromaticity of the retinal image are considered. Such optical effects have important methodological and(More)
Myopia is the commonest ocular abnormality but as a research topic remains at the margins of mainstream ophthalmology. The concept that most myopes fall into the category of 'physiological myopia' undoubtedly contributes to this position. Yet detailed analysis of epidemiological data linking myopia with a range of ocular pathologies from glaucoma to retinal(More)
The purpose of this work was to investigate quantitatively the interactions between accommodation, vergence and a mechanism of emmetropization driven by optical blur within the retinal image with a view to developing a model that provides an explanation of both normal emmetropization and near-work associated myopia. The simulations of the change in the(More)
Accommodation is more accurate with polychromatic stimuli than with narrowband or monochromatic stimuli. The aim of this paper is to develop a computational model for how the visual system uses the extra information in polychromatic stimuli to increase the accuracy of accommodation responses. The proposed model is developed within the context of both(More)
PURPOSE The authors applied partial coherence interferometry (PCI) to estimate the thickness of the human choroid in vivo and to learn whether it fluctuates during the day. METHODS By applying signal processing techniques to existing PCI tracings of human ocular axial length measurements, a signal modeling algorithm was developed and validated to(More)
Static accommodation responses to sinusoidal grating stimuli that displayed temporal modulations in luminance contrast (i.e. contrast flicker) were measured with a laser speckle optometer. The effects of a variety of temporal waveforms were investigated including square-wave modulations, sinusoidal modulations, and band-pass filtered noise. The effects of(More)
The lens-rearing paradigm has developed great importance in the field of experimental myopia. Although an apparently simple paradigm, the results of any experiment can be influenced by a variety of factors including habitual viewing distance, ocular refraction, oculomotor performance and the spatial sensitivity of the retinal elements involved in retinal(More)
AIMS To evaluate the relation between refractive error and electrophysiological retinal abnormalities in children referred for investigation of reduced vision. METHODS The study group comprised 123 consecutive patients referred over a 14 month period from the paediatric service of Moorfields Eye Hospital for electrophysiological investigation of reduced(More)
PURPOSE This study sought diurnal variations of eye length in human subjects, analogous to those reported in laboratory animals. METHODS Seventeen subjects, ages 7 to 53 (median 16) years and mean spherical equivalent refractive error -0.68 D (range, -3.00 to +1.00 D), underwent axial length measurements at multiple times during the day between 7 AM and 1(More)
INTRODUCTION To learn if eye shape might be a useful parameter in refractive research. MATERIALS AND METHODS Laboratory research on eye growth mechanisms is summarised. The available clinical literature relating refraction to eye shape and peripheral refraction is critically assessed in the context of the laboratory research on refractive development. (More)