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- D. Hug, R. Schneider
- 2005

We establish a close relationship between isoperimetric inequalities for convex bodies and asymptotic shapes of large random polytopes, which arise as cells in certain random mosaics in d-dimensional Euclidean space. These mosaics are generated by Poisson hyperplane processes satisfying a few natural assumptions (not necessarily sta-tionarity or isotropy).… (More)

- Daniel Hug, Rolf Schneider
- 2004

The principal kinematic formula and the closely related Crofton formula are central themes of integral geometry in the sense of Blaschke and Santaló. There have been various generalizations , variants, and analogues of these formulae, in part motivated by applications. We give a survey of recent investigations in the spirit of the kinematic and Crofton… (More)

We consider geometric functionals of the convex hull of normally distributed random points in Eu-clidean space R d. In particular, we determine the asymptotic behaviour of the expected value of such functionals and of related geometric probabilities, as the number of points increases.

This paper originates from the investigation of support measures of convex bodies (sets of positive reach), which form a central subject in convex geometry and also represent an important tool in related fields. We show that these measures are absolutely continuous with respect to Hausdorff measures of appropriate dimensions, and we determine the… (More)

For a given convex (semi-convex) function u, defined on a nonempty open convex set Ω ⊂ R n , we establish a local Steiner type formula , the coefficients of which are nonnegative (signed) Borel measures. We also determine explicit integral representations for these coefficient measures, which are similar to the integral representations for the curvature… (More)

- M H Binger, D Hug, G Weber, E Schildknecht, M Hümbelin, L Pasamontes
- Molecular and biochemical parasitology
- 1993

A rabbit serum raised against Eimeria tenella merozoites was used to screen a lambda gt11 cDNA library made from merozoite mRNA of E. tenella. The insert of the phage clone lambda Mz 5-7 revealed an open reading frame consisting of 945 nucleotides, encoding a 33-kDa protein. This size is consistent with the size of a protein translated in vitro from… (More)

- Angela Broggini-Tenzer, Ashish Sharma, +6 authors Martin Pruschy
- Journal of the National Cancer Institute
- 2015

BACKGROUND
Resistance to microtubule-stabilizing agents is a major hurdle for successful cancer therapy. We investigated combined treatment of microtubule-stabilizing agents (MSAs) with inhibitors of angiogenesis to overcome MSA resistance.
METHODS
Treatment regimens of clinically relevant MSAs (patupilone and paclitaxel) and antiangiogenic agents… (More)

- L Pasamontes, D Hug, M Tessier, H P Hohmann, J Schierle, A P van Loon
- Gene
- 1997

The Gram-negative bacterium Flavobacterium sp. strain R1534 is a natural producer of zeaxanthin. A 14 kb genomic DNA fragment of this organism has been cloned and a 5.1 kb piece containing the carotenoid biosynthesis genes sequenced. The carotenoid biosynthesis cluster consists of five genes arranged in at least two operons. The five genes are necessary and… (More)

- Katrin Orlowski, Carla Rohrer Bley, +5 authors Martin Pruschy
- PloS one
- 2012

Tumor hypoxia is one of the most important parameters that determines treatment sensitivity and is mainly due to insufficient tumor angiogenesis. However, the local oxygen concentration in a tumor can also be shifted in response to different treatment modalities such as cytotoxic agents or ionizing radiation. Thus, combined treatment modalities including… (More)

- Daniel Hug, Erwin Lutwak, Deane Yang, Gaoyong Zhang
- Discrete & Computational Geometry
- 2005

Two new approaches are presented to establish the existence of polytopal solutions to the discrete-data L p Minkowski problem for all p > 1. As observed by Schneider [21], the Brunn-Minkowski theory springs from joining the notion of ordinary volume in Euclidean d-space, R d , with that of Minkowski combinations of convex bodies. One of the cornerstones of… (More)