Daniel Hötzel

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The authors discuss changes in macro- and micro-nutrients which occur in weightlessness and consider factors which help maintain appropriate nutrition during extended space flight. Basic energy requirements and metabolism are reviewed. The discussion of handling of foodstuffs includes protein, fats, carbohydrates, vitamins, folic acid, iron, and selenium.(More)
The effect of different dietary intake of pantothenic acid (150;100;25 and 0% of the requirement) on the metabolism of rats was studied during 15 months. The ability of the adrenals for synthesis of corticosterone and the rate of acetylation of a sulfonamid (Sulfisomidin) were taken as parameters. The above mentioned parameters were influenced significantly(More)
In a study on 250 industrial workers the amount of the formiminoglutamic acid excretion in urine was measured by an enzymatic spectrophotometric method. For the estimation of the folacine status the vitamine concentration in serum and erythrozytes was determined as well as the segmentation of the neutrophilic granulocytes. As shown in previous studies these(More)
Methods and Their Evaluation to Estimate the Vitamin B6-Status in Human Subjects. V. S-PLP-Determination: Method and Comparison of Methods. A method to determine the plasma pyridoxal 5-phosphate (PLP) basing on the enzymatic decarboxylation of 1-14C-l-tyrosine and the measurement of the radio-active 14CO2 is described. Its efficiency is discussed in(More)
Osteoporosis is a bone disease of great sociomedical and economic importance. Postmenopausal women are primarily affected. Pathogenesis is of multifactorial origin. In Western countries, reduced physical activity and an inadequate nutritional calcium supply are important aspects besides decreased postmenopausal oestrogen secretion. Food statistics confirm(More)
In a study on 130 student volunteers the segmentation of neutrophil granulocytes was measured. The serum folate concentration was used as biochemical reference. Both parameters indicate the state of folate supply or the degree of folate deficiency, respectively. Considering the haematologic response as an objective criterion only 71% of the examines showed(More)
In a study of apparently healthy volunteers (5 male, 5 female) the bioavailability of iron and folacin was calculated using Tardyferon¿ resp. Tardyferon-Fol¿ as test substances. Blood samples for serum iron and folacin level determinations were obtained before and 1/2, 1, 2, 4, 6 and 8 hours after dosing. Because of the diurnal fluctuation of serum iron and(More)