BACKGROUND We report the main findings of the WHO Multicountry Survey on Maternal and Newborn Health (WHOMCS), which aimed to assess the burden of complications related to pregnancy, the coverage of key maternal health interventions, and use of the maternal severity index (MSI) in a global network of health facilities. METHODS In our cross-sectional… (More)
BACKGROUND Caesarean delivery rates continue to increase worldwide. Our aim was to assess the association between caesarean delivery and pregnancy outcome at the institutional level, adjusting for the pregnant population and institutional characteristics. METHODS For the 2005 WHO global survey on maternal and perinatal health, we assessed a multistage… (More)
OBJECTIVE To assess the risks and benefits associated with caesarean delivery compared with vaginal delivery. DESIGN Prospective cohort study within the 2005 WHO global survey on maternal and perinatal health. SETTING 410 health facilities in 24 areas in eight randomly selected Latin American countries; 123 were randomly selected and 120 participated… (More)
BACKGROUND Control of blood glucose is important in reducing both the incidence and the severity of complications in diabetes mellitus. One consequence of long- term hyperglycaemia is the formation and accumulation of advanced glycation end-products (AGEs) on tissue macromolecules. An AGE-modified form of human haemoglobin (Hb-AGE) present at high levels in… (More)
BACKGROUND Perinatal mortality and morbidity continue to be major global health challenges strongly associated with prematurity and reduced fetal growth, an issue of further interest given the mounting evidence that fetal growth in general is linked to degrees of risk of common noncommunicable diseases in adulthood. Against this background, WHO made it a… (More)
[This corrects the article DOI: 10.1371/journal.pmed.1002220.].
BACKGROUND Every year millions of women around the world suffer from pregnancy, childbirth and postpartum complications. Women who survive the most serious clinical conditions are regarded as to have experienced a severe acute maternal complication called maternal near miss (MNM). Information about MNM cases may complement the data collected through the… (More)