Daniel Geppert

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Matrix metalloproteinases (MMPs) are a family of zinc endopeptidases that have been implicated in various disease processes. Different classes of MMP inhibitors, including hydroxamic acids, phosphinic acids and thiols, have been previously described. Most of these mimic peptides and most likely bind in a similar way to the corresponding peptide substrates.(More)
BACKGROUND The oesophageal leak pressure is defined as the pressure which breaks the seal between the cuff of a supraglottic airway and the peri-cuff mucosa, allowing penetration of fluid into the pharynx and the oral cavity. As a consequence, a decrease in this variable increases the risk of reflux and can lead to pulmonary aspiration. The aim of this(More)
The NOMAD experiment is currently collecting data at the CERN SPS. The detector is now being completed, as speciied in the original proposal, and has been further improved. All subdetectors are functioning well. The experiment is searching for ! neutrino oscillations and is sensitive to the mass diierence squared m 2 > 0:7 eV 2. Maximal sensitivity with(More)
We report the rst precision measurements of the scaled momentum, the charge multi-plicity, and the thrust of hadronic jets in the Breit frame in Deep Inelastic Scattering N and N charged current events over the Q 2 range from 1 to 100 GeV 2. The neutrino data, obtained in the NOMAD experiment at the CERN SPS, extend the Q 2-evolution of these parameters by(More)
AIMS To determine the association between ambient temperature and severe hypoglycemia. METHODS This was a prospective observational study performed in a prehospital setting. Data from the Emergency Medical Service in Hamburg (Germany) and data from the local weather station were evaluated over a 5-year period. Lowess-regression analysis was conducted to(More)
OBJECTIVE To test the hypothesis that more cardiovascular emergencies occur at low rather than at high temperatures under moderate climatic conditions. METHODS This was a prospective observational study performed in a prehospital setting. Data from the Emergency Medical Service in Hamburg (Germany) and from the local weather station were evaluated over a(More)
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