Daniel G Foster

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Spinal muscular atrophy (SMA), the leading genetic disorder of infant mortality, is caused by low levels of survival motor neuron (SMN) protein. Currently it is not clear how the SMN protein levels are regulated at the post-transcriptional level. In this report, we find that Usp9x, a deubiquitinating enzyme, stably associates with the SMN complex via(More)
Low levels of the survival motor neuron (SMN) protein cause spinal muscular atrophy, the leading genetic disorder for infant mortality. SMN is ubiquitously expressed in various cell types and localizes in both the cytoplasm and the nucleus, where it concentrates in two subnuclear structures termed Cajal body (CB) and gems. In addition, SMN can also be(More)
  • Terry Cross, Matt Morton, Melissa Clyde, Kristy Alberty Government, Affairs Associate, Ashley Horne +9 others
  • 2009
for reviewing the toolkit's content; and Jocelyn Formsma for her poem on suicide issues. Copies of this publication are available to download at www.nicwa.org. COVER ARTWORK Healthy activities, like writing poetry, to express complicated emotions can prove helpful for youth impacted by suicide. The poem fragment on the cover is from such a poem, which is(More)
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