Daniel Fernández

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A/B-type metallocarboxypeptidases (MCPs) are among the most thoroughly studied proteolytic enzymes, and their catalytic mechanisms have been considered as prototypes even for several unrelated metalloprote(in)ase families. It has long been postulated that the nature of the side chains of at least five substrate residues, i.e., P4-P1', influence Km and kcat(More)
Protein aggregation correlates with the development of several deleterious human disorders such as Alzheimer's disease, Parkinson's disease, prion-associated transmissible spongiform encephalopathies and type II diabetes. The polypeptides involved in these disorders may be globular proteins with a defined 3D-structure or natively unfolded proteins in their(More)
This paper describes a method for estimating the vehicle global position in a network of roads by means of visual odometry. To do so, the ego-motion of the vehicle relative to the road is computed using a stereo-vision system mounted next to the rear view mirror of the car. Feature points are matched between pairs of frames and linked into 3D trajectories.(More)
In this paper we present an electronic circuit for position or capacitance estimation of MEMS electrostatic actuators based on a switched capacitor technique. The circuit uses a capacitive divider configuration composed by a fixed capacitor and the variable capacitance of the electrostatic actuator for generating a signal that is a function of the input(More)
There exist many portal servers that support the construction of "My" portals that is portals that allow the user to have one or more personal pages composed of a number of personalizable services. The main drawback of current portal servers is their lack of generality and adaptability. This paper presents the design of MyPersonalizer a J2EE-based framework(More)
—A fully CMOS-compatible translinear element which precisely follows the exponential relation between its input control voltage and output current over more than seven decades of the output current is presented. A statistical analysis of the I-V characteristic of 75 manufactured translinear elements reveals good matching behavior. The proposed translinear(More)