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  • Daniel E. Kaufmann, Daniel G. Kavanagh, +18 authors Bruce D. Walker
  • Medicine, Biology
  • Nature Immunology
  • 2007 (First Publication: 1 November 2007)
  • In progressive viral infection, antiviral T cell function is impaired by poorly understood mechanisms. Here we report that the inhibitory immunoregulatory receptor CTLA-4 was selectively upregulatedContinue Reading
  • Mathias Lichterfeld, Daniel E. Kaufmann, +12 authors Marcus Altfeld
  • Medicine
  • The Journal of experimental medicine
  • 2004 (First Publication: 20 September 2004)
  • Virus-specific CD8+ T cells are associated with declining viremia in acute human immunodeficiency virus (HIV)1 infection, but do not correlate with control of viremia in chronic infection, suggestingContinue Reading
  • Todd M. Allen, Marcus Altfeld, +19 authors Bruce D. Walker
  • Biology, Medicine
  • Journal of virology
  • 2005 (First Publication: 1 November 2005)
  • The sequence diversity of human immunodeficiency virus type 1 (HIV-1) represents a major obstacle to the development of an effective vaccine, yet the forces impacting the evolution of this pathogenContinue Reading