Daniel E. Weibel

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OBJECTIVE To assess the association between pandemic influenza A (H1N1) 2009 vaccine and Guillain-Barré syndrome. DESIGN Case-control study. SETTING Five European countries. PARTICIPANTS 104 patients with Guillain-Barré syndrome and its variant Miller-Fisher syndrome matched to one or more controls. Case status was classified according to the Brighton(More)
BACKGROUND The risk of Guillain-Barré syndrome (GBS) following the United States' 1976 swine flu vaccination campaign in the USA led to enhanced active surveillance during the pandemic influenza (A(H1N1)pdm09) immunization campaign. This study aimed to estimate the risk of GBS following influenza A(H1N1)pdm09 vaccination. METHODS A self-controlled case(More)
BACKGROUND Better evidence regarding drug safety in the pediatric population might be generated from existing data sources such as spontaneous reporting systems and electronic healthcare records. The Global Research in Paediatrics (GRiP)-Network of Excellence aims to develop pediatric-specific methods that can be applied to these data sources. A reference(More)
INTRODUCTION Spontaneous reports of suspected adverse drug reactions (ADRs) can be analyzed to yield additional drug safety evidence for the pediatric population. Signal detection algorithms (SDAs) are required for these analyses; however, the performance of SDAs in the pediatric population specifically is unknown. We tested the performance of two SDAs on(More)
PURPOSE In order to identify challenges in pediatric pharmacoepidemiological safety studies, we assessed the characteristics of such (published) studies. METHODS Relevant articles from inception to 2013 were retrieved from Embase and Medline. We sequentially screened titles, abstracts and full texts with independent validation. We systematically collected(More)
OBJECTIVES To investigate disease history before A(H1N1)pdm09 vaccination as a risk factor for narcolepsy. METHODS Case-control study in Sweden. Cases included persons referred for a Multiple Sleep Latency Test between 2009 and 2010, identified through diagnostic sleep centres and confirmed through independent review of medical charts. Controls, selected(More)
The surface of Poly(sulfone) (PSU) and Polyurethane (PU) films were treated with ultraviolet (UV) light in the presence of oxygen to improve their wettability, adhesion and cell spreading properties. XPS and WCA results illustrated the effective conversion of the PSU and PU surfaces from hydrophobic to hydrophilic with grafting of new oxidized functional(More)
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