Multiple sclerosis (MS) is a chronic disease of the central nervous system responsible for a large portion of neurological disabilities in young adults. Similar to what occurs in numerous complex diseases, both unknown environmental factors and genetic predisposition are required to generate MS. We ascertained a set of 63 Finnish MS families, originating… (More)
A novel approach to finding candidate genes by using gene expression data through liquid association is developed and used to identify multiple sclerosis susceptibility candidate genes.
RATIONALE Exacerbations of COPD are defined clinically by worsening of chronic respiratory symptoms. Chronic respiratory symptoms are common in the general population. There are no data on the frequency of exacerbation-like events in individuals without spirometric evidence of COPD. AIMS To determine the occurrence of 'exacerbation-like' events in… (More)
Background. The incidence of hepatitis C virus (HCV) infection is increasing in human immunodeficiency virus (HIV)-positive men who have sex with men (MSM). New guidelines recommend annual screening for HCV, similar to recommendations for syphilis screening with rapid plasma reagin (RPR). Methods. This study compares the frequency of repeat HCV antibody… (More)
This paper tests the hypothesis that pre-modern textile production leads to greater gender equality. I exploit variation in pre-modern textiles at the county level to identify their effects on gender equality since 1300. I find despite the the lack of benefits of working outside home, places where women were more productive in textile production developed… (More)
The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Abstract Internet search engines display advertisements along with search results, providing them with a major source of revenue. The display of ads is triggered by the use of keywords, which are found in the searches performed by search… (More)
This article examines the driving factors that account for patterns of linkages to broader economic, labor, environmental, and security issues in U.S. Free Trade Agreements (FTAs). Rather than only emphasizing trade benefits or security considerations as in much recent work on FTAs, this analysis provides a richer empirical picture by focusing on the full… (More)