Porcine reproductive and respiratory syndrome virus (PRRSV) causes chronic, economically devastating disease in pigs of all ages. Frequent mutations in the viral genome result in viruses with immune escape mutants. Irrespective of regular vaccination, control of PRRSV remains a challenge to swine farmers. In PRRSV-infected pigs, innate cytokine IFN-α is… (More)
Porcine reproductive and respiratory syndrome virus (PRRSv) is a swine-specific pathogen that causes significant increases in production costs. When a breeding herd becomes infected, in an attempt to hasten control and elimination of PRRSv, some veterinarians have adopted a strategy called load-close-expose which consists of interrupting replacement pig… (More)
these strains are most similar to strains characterized in 2014–2015 in Brazil, which were associated with idiopath-ic vesicular disease and neonatal death. Little diagnostic testing is performed on culled animals, which may in part explain the discrepancy between 1% of oral fluids submitted for diagnostic testing being positive for SVA (7), compared with… (More)
In the title of the article, the word " Vaccination " should be " Immunization. " The correct title is: Economic Analysis of Immunization Strategies for PRRS Control. The correct citation is: There is an error in the seventh sentence of the Abstract. The correct sentence is: Preventive vaccination of sow herds was beneficial when the frequency of PRRSv… (More)
Since July 2015, vesicular lesions affecting growing pigs and sows accompanied with neonatal mortality have been reported in multiple U.S. states. Senecavirus A has been consistently detected from these cases. The complete genome sequences of 3 recent U.S. Senecavirus A isolates were determined to further characterize this virus.