Daniel Binder

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The hematologic consequences of infection with the noncytopathic lymphocytic choriomen-ingitis virus (LCMV) were studied in wild-type mice with inherent variations in their inter-feron (IFN)-␣ / ␤ responder ability and in mutant mice lacking ␣ / ␤ (IFN-␣ / ␤ R 0/0) or ␥ IFN (IFN-␥ R 0/0) receptors. During the first week of infection, wild type mice(More)
Aplastic anemia may be associated with persistent viral infections that result from failure of the immune system to control virus. To evaluate the effects on hematopoiesis exerted by sustained viral replication in the presence of activated T cells, blood values and bone marrow (BM) function were analyzed in chronic infection with lymphocytic(More)
Lung cancer is one of the leading causes of death in industrialized and developing countries. Approximately 80% of patients are diagnosed with non-small cell histology. Although a multidisciplinary approach is necessary for the treatment of patients at early or locally-advanced stages of the disease, further successes in the treatment of patients with(More)
Engineers in the automotive domain are confronted with a huge load of information making it difficult for them to identify the information relevant for performing their tasks. Particularly challenging is the alignment of process information, such as offices files, checklists, and guidelines with business processes. In previous work, we introduced the(More)
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