Danbing Seto

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Most real-time computer-controlled systems are built in two separate steps, each in isolation: controller design and its digital implementation. Computational tasks that realize the control algorithms are usually scheduled by treating their execution times and periods as unchangeable parameters. Task scheduling therefore depends only on the limited(More)
In many real-time applications, especially those involving computer-controlled systems, the application tasks often have a maximal acceptable latency, and small latency is preferred to large. The interaction between choosing task periods to meet the individual latency requirements and scheduling the resulting task set was investigated in [4] using dynamic(More)
In this paper, we describe the Simplex architecture, a real-time software technology which supports the safe, reliable introduction of control system upgrades while the system is running. We present the Simplex architecture from a control application point of view. In particular, we discuss the fault-tolerance feature of the technology, introduce its basic(More)
The characteristic pathological features of the postmortem brain of Alzheimer's disease (AD) patients include, among other features, the presence of neuritic plaques composed of amyloid beta-peptide (A beta) and the loss of basal forebrain cholinergic neurons, which innervate the hippocampus and the cortex. Studies of the pathological changes that(More)
Insulin-like growth factors-I and -II (IGF-I and -II) are structurally related mitogenic polypeptides with potent growth promoting effects. These peptides and their corresponding IGF-I and -II receptors are selectively localized in the brain. To date, most of the effects of IGFs are believed to be mediated by IGF-I receptors whereas the significance of(More)
Administration of kainic acid evokes acute seizure in hippocampal pathways that results in a complex sequence of functional and structural alterations resembling human temporal lobe epilepsy. The structural alterations induced by kainic acid include selective loss of neurones in CA1-CA3 subfields and the hilar region of the dentate gyrus followed by(More)
Comparative genomics is enhanced by data mining the rapidly expanding DNA sequence databases. Because of the immense amount of data, computational tools and methods are needed to augment traditional manual visualizations and manipulations of these data. GeneOrder2.0, a Java-based interactive software programme, organizes genome sequence data into tabular(More)
Evidence suggests that insulin-like growth factor-I (IGF-I) plays an important role during brain development and in the maintenance of normal as well as activity-dependent functioning of the adult brain. Apart from its trophic effects, IGF-I has also been implicated in the regulation of brain neurotransmitter release thus indicating a neuromodulatory role(More)
Most real-time computer-controlled systems are developed in two separate stages: controller design followed by its digital implementation. Computational tasks that implement the control algorithms are usually scheduled by treating their execution times and periods as unchangeable parameters. Task schedulability therefore depends only on the limited(More)
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