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To examine the influence of chronic mechanical stretch on functional behavior of cardiac myocytes, we reconstituted embryonic chick or neonatal rat cardiac myocytes to a 3-dimensional engineered heart tissue (EHT) by mixing freshly isolated cells with neutralized collagen I and culturing them between two Velcro-coated silicone tubes, held at a fixed(More)
The world is facing a tremendous resource supply challenge. One strategy of regions and nations to address this issue is to encourage research and innovation through funding programs. Most of the time, these programs require that research and innovation projects quantify potential increases in resource efficiency achieved by the projects. However, no(More)
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