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Micelles and vesicles coexist in native bile. Mixed micelles are composed of bile salt, phospholipid, and cholesterol. Micellar bile salt is in equilibrium with the aqueous phase bile salt (intermicellar bile salt), and mixed micelles can be converted to cholesterol-phospholipid vesicles by depletion of bile salt. To determine the amount of cholesterol(More)
We focus on a fully implicit, nonlinearly converged, solution of multimaterial equilibrium radiation diffusion problems. The nonlinear method of solution is a Newton–Krylov (generalized minimum residual, GMRES) method preconditioned by a multigrid method. The multigrid iteration matrix results from a Picard-type linearization of the governing equations. The(More)