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Effectiveness of convalescent plasma therapy in severe COVID-19 patients
Significance COVID-19 is currently a big threat to global health. However, no specific antiviral agents are available for its treatment. In this work, we explore the feasibility of convalescentExpand
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Identification and Characterization of an Epi-Allele of FIE1 Reveals a Regulatory Linkage between Two Epigenetic Marks in Rice[W][OA]
This work identifies an epi-allele of rice Fertilization Independent Endosperm1 (FIE1) with DNA hypomethylation, reduced H3 Lys 9 dimethylation, increased H3 Lys 4 trimethylation, ectopic FIE1Expand
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SARS-CoV-2 proteome microarray for mapping COVID-19 antibody interactions at amino acid resolution
COVID-19 has quickly become a worldwide pandemic, which has significantly impacted the economy, education, and social interactions. Understanding the humoral antibody response to SARS-CoV-2 proteinsExpand
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An Enterotoxin-Bearing Pathogenicity Island in Staphylococcus epidermidis.
Cocolonization of human mucosal surfaces causes frequent encounters between various staphylococcal species, creating opportunities for the horizontal acquisition of mobile genetic elements. TheExpand
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A Single Polymorphism in HIV-1 Subtype C SP1 Is Sufficient To Confer Natural Resistance to the Maturation Inhibitor Bevirimat
ABSTRACT 3-O-(3′,3′-Dimethylsuccinyl) betulinic acid (DSB), also known as PA-457, bevirimat (BVM), or MPC-4326, is a novel HIV-1 maturation inhibitor. Unlike protease inhibitors, BVM blocks theExpand
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The role of NLRP3 inflammasome in infection-related, immune-mediated and autoimmune skin diseases.
Inflammasomes are large intracellular multi-protein signaling complexes which are responsible for the activation of inflammatory responses. Among multifarious subtypes of inflammasomes, NLRP3 hasExpand
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CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors
The development of clustered regularly interspaced short-palindromic repeat (CRISPR)-based biotechnologies has revolutionized the life sciences and introduced new therapeutic modalities with theExpand
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Molecular Basis of Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS Gene-Gene Interaction Involved in Atrial Fibrillation
Atrial fibrillation (AF) is the most common cardiac arrhythmia at the clinic. Recent GWAS identified several variants associated with AF, but they account for <10% of heritability. Gene-geneExpand
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Proteome-wide analysis of differentially-expressed SARS-CoV-2 antibodies in early COVID-19 infection
Rapid and accurate tests that detect IgM and IgG antibodies to SARS-CoV-2 proteins are essential in slowing the spread of COVID-19 by identifying patients who are infected with COVID-19. Using aExpand
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Expression of open reading frames in silkworm pupal cDNA library
  • Y. Zhang, J. Chen, +8 authors X. Wu
  • Biology, Medicine
  • Applied biochemistry and biotechnology
  • 1 March 2007
A cDNA library containing 2409 singletons was constructed from whole silkworm pupae (Bombyx mori) In addition, the types of genes overexpressed in pupa were analyzed. These genes contained 79 typesExpand
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