• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage your publications. Semantic Scholar automatically creates author pages based on data aggregated from public sources and our publisher partners.
  • Stuart A. Scott, Katrin Sangkuhl, +7 authors Alan R. Shuldiner
  • Medicine
  • Clinical pharmacology and therapeutics
  • 2013 (First Publication: 1 September 2013)
  • Cytochrome P450 (CYP)2C19 catalyzes the bioactivation of the antiplatelet prodrug clopidogrel, and CYP2C19 loss-of-function alleles impair formation of active metabolites, resulting in reducedExpand
  • Björn C Knollmann, Nagesh Chopra, +12 authors Karl Pfeifer
  • Biology, Medicine
  • The Journal of clinical investigation
  • 2006 (First Publication: 24 August 2006)
  • Cardiac calsequestrin (Casq2) is thought to be the key sarcoplasmic reticulum (SR) Ca2+ storage protein essential for SR Ca2+ release in mammalian heart. Human CASQ2 mutations are associated withExpand
  • Stuart A. Scott, Katrin Sangkuhl, +6 authors Alan R. Shuldiner
  • Medicine
  • Clinical pharmacology and therapeutics
  • 2011 (First Publication: 1 August 2011)
  • CYP2C19 is one of the principal enzymes involved in the bioactivation of the antiplatelet prodrug clopidogrel. A common loss-of-function allele, CYP2C19*2 (c.681G>A; rs4244285), is associated withExpand