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Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for motoneurons (MNs), and is considered a potential agent for the treatment of amyotrophic lateral sclerosis (ALS) and other MN diseases. The effectiveness of GDNF may depend significantly upon its route of delivery to MNs. In this study we tested the neuroprotective effects of(More)
Analogy plays a central role in legal reasoning, yet how to analogize is poorly taught and poorly practiced. We all recognize when legal analogies are being made: when a law professor suggests a difficult hypothetical in class and a student tentatively guesses at the answer based on the cases she read the night before, when an attorney advises a client to(More)
Australia’s decision to implement Internet censorship using technological means creates a natural experiment: it can become the first Western democracy to mandate filtering legislatively and to retrofit it to a decentralized network. But are the proposed restrictions legitimate? The new restraints derive from the Labor Party’s pro-filtering electoral(More)
Imagination involves episodic memory retrieval, visualization, mental simulation, spatial navigation, and future thinking, making it a complex cognitive construct. Prior studies of imagination have attempted to study various elements of imagination (e.g., visualization), but none have attempted to capture the entirety of imagination ability in a single(More)
Total quality management (TQM) or continuous quality improvement (CQI) are terms no longer being used exclusively within the manufacturing industry sector. Health care facilities, such as hospitals and nursing homes, are beginning to actively compete with each other for patients as well as face new regulations from the government. Hence, it is imperative(More)