Damon J. A. Toth

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Influenza poses a significant health threat to children, and schools may play a critical role in community outbreaks. Mathematical outbreak models require assumptions about contact rates and patterns among students, but the level of temporal granularity required to produce reliable results is unclear. We collected objective contact data from students aged(More)
BACKGROUND Clostridium difficile is one of the most common and important nosocomial pathogens, causing severe gastrointestinal disease in hospitalized patients. Although "bundled" interventions have been proposed and promoted, optimal control strategies remain unknown. METHODS We designed an agent-based computer simulation of nosocomial C. difficile(More)
Anthrax poses a community health risk due to accidental or intentional aerosol release. Reliable quantitative dose-response analyses are required to estimate the magnitude and timeline of potential consequences and the effect of public health intervention strategies under specific scenarios. Analyses of available data from exposures and infections of humans(More)
Wireless sensor networks (WSNs) have come a long way to reach their ubiquitous state known today through scalable cost, low-power optimizations, and data management. As WSNs scale in size, the necessity for system designs - from low-level hardware implementations to data collection and management procedures - to account for handling extensive amounts of(More)
While the ongoing Ebola outbreak continues in the West Africa countries of Guinea, Sierra Leone, and Liberia, health officials elsewhere prepare for new introductions of Ebola from infected evacuees or travelers. We analyzed transmission data from patients (i.e., evacuees, international travelers, and those with locally acquired illness) in countries other(More)
Estimates of contact among children, used for infectious disease transmission models and understanding social patterns, historically rely on self-report logs. Recently, wireless sensor technology has enabled objective measurement of proximal contact and comparison of data from the two methods. These are mostly small-scale studies, and knowledge gaps remain(More)
INTRODUCTION Network projections of data can provide an efficient format for data exploration of co-incidence in large clinical datasets. We present and explore the utility of a network projection approach to finding patterns in health care data that could be exploited to prevent homelessness among U.S. Veterans. METHOD We divided Veteran ICD-9-CM (ICD9)(More)
reproduction in any medium, provided the original work is properly cited. Objective To enhance public health surveillance and response for acute respiratory infectious diseases by understanding social contacts among school-aged children Introduction Timely and effective public health decision-making for control and prevention of acute respiratory infectious(More)
We model a chemostat containing an age-structured predator and its prey using a linear function for the uptake of substrate by the prey and two different functional responses (linear and Monod) for the consumption of prey by the predator. Limit cycles (LCs) caused by the predator's age structure arise at Hopf bifurcations at low values of the chemostat(More)
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