Damien Kennedy

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Although the hippocampus is a key brain region in the pathophysiology of schizophrenia, it is unclear whether structural or biochemical abnormalities predate illness onset. In this study, we used magnetic resonance imaging and spectroscopy data acquired prior to both the onset of psychosis and treatment with antipsychotics to determine this. Sixty-six young(More)
Growing evidence indicates that nonpsychotic relatives of patients with schizophrenia have subtle brain abnormalities in limbic, paralimbic and cortical regions. Verbal memory deficits in adult relatives have also been demonstrated. In this study we present more comprehensive morphomet-ric analyses of the limbic and paralimbic cortices, to test the(More)
The purpose of this study involving a sample of children with single central incisor crossbite was to determine the relationship between clinical crown lengths of the crossbite and noncrossbite mandibular incisors, incisor irregularity, and orthodontic correction of the crossbite. In addition, for comparison, the normal maturational change in position of(More)
OBJECTIVES (1) To assess the acceptability of a gel solution of adrenaline (epinephrine) (1 in 2000) and cocaine (5%) for anaesthetising children's facial lacerations to the child, parent, and operator. (2) To assess the safety of the current protocol. SETTING The emergency unit of a large university hospital. METHODS All patients who were treated with(More)
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