Damien Dufournel

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The aim of our study was to assess abnormalities in 5-hydroxytryptamine-1A (5-HT1A) receptor density in patients suffering from refractory temporal lobe epilepsy (TLE). Experimental data in animals show that 5-HT1A receptors are predominantly located in limbic areas, and that serotonin, via these receptors, mediates an antiepileptic and anticonvulsant(More)
Experimental data in animals show that 5-HT(1A) receptors are predominantly located in limbic areas and suggest that serotonin, via these receptors, mediates an antiepileptic and anticonvulsant effect. In this PET study, we used an antagonist of the 5-HT(1A) receptor, [(18)F]MPPF, to assess the extent of 5-HT(1A) receptor binding changes in a group of seven(More)
F. Cervenansky, D. Dufournel, N. Costes, P. Ryvlin, D. Sappey-Marinier CERMEP, Université Claude Bernard, Lyon, France, CERMEP, CNRS, Lyon, France, Neurology hospital, Lyon, France Synopsis With the advent of high resolution MRI, malformations of cortical development (MCD) are increasingly detected and recognized as the underlying cause of seizure in(More)
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