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Rats ate voraciously after intraventricular injections of the alpha-noradrenergic receptor stimulant clonidine. Intraventricular administration of l-norepinephrine also facilitated feeding, but similar injections of dopamine and apomorphine (a dopamine receptor stimulant) were ineffective and even tended to suppress feeding. Clonidine was 100 times more(More)
This paper presents reliable high power and high brightness 9xx-nm single emitter laser diodes, which have been designed for various multi-emitter fiber-coupled modules. Diode lasers from legend generation have been life-tested with currents up to 14A at heat-sink and junction temperatures of 50°C and 80°C respectively, and have accumulated more than 15,000(More)
Although slipped capital femoral epiphysis is the most common disorder of the hip in adolescents, the diagnosis is often delayed. The subsequent development of degenerative joint disease is related to the severity of the slip, which in turn is usually related to the duration of the symptoms. This article summarizes the aetiology, epidemiology, clinical(More)
Sir, Recently there has been considerable discussion over the role of a national curriculum in general practice vocational training.12 All general practitioners have special interests, but it is still essential that they should have an adequate education in all aspects of medicine in order to act effectively as the first line of treatment for their(More)
We report on recent progress in the control of optical modes toward the improvement of commercial high-performance diode laser modules. Control of the transverse mode has allowed scaling of the optical mode volume, increasing the peak output power of diode laser emitters by a factor of two. Commercially-available single emitter diodes operating at 885 nm(More)
Improved performance and reliability of 9xx nm single emitter laser diodes are presented. To date, over 15,000 hours of accelerated multi-cell lifetest reliability data has been collected, with drive currents from 14A to 18A and junction temperatures ranging from 60C to 110C. Out of 208 devices, 14 failures have been observed so far. Using established(More)
Peak optical power from single 1-cm diode laser bars is advancing rapidly across all commercial wavelengths. Progress in material performance is reviewed and we show that current trends imply there is no fundamental barrier to achieving peak powers of 1-kW per 1-cm diode laser bar. For bars with such high peak powers, commercially available reliable devices(More)