Damián Martínez-Muñoz

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The anticonvulsant activity of a homologous series of phenyl alcohol amides is described. (+-)-2-Hydroxy-2-phenylbutyramide (1), (+-)-3-hydroxy-3-phenylpentanamide (2) and (+-)-4-hydroxy-4-phenylhexanamide (3) were prepared and tested for their anticonvulsant profile and neurotoxicity. 1, 2 and 3 exhibited a broad profile of anticonvulsant activity and a(More)
  • P J Reche-López, N Ruiz-Reyes, P Vera-Candeas, D Martínez-Muñoz, J C Cuevas-Martínez
  • 2004
A preliminary investigation of an atomic model-based algorithm for the compression of single lead ECG is presented. The paper presents a novel coding scheme for ECG signals based on time-frequency atomic signal representations. Signal-adaptive parametric models based on overcomplete dictionaries of time-frequency atoms are considered. Such overcomplete(More)
This paper deals with the modifications of the audio signal in a parametric audio coder at the decoder stage. The parametric audio coder is based on the application of adaptive signal models for each audio signal component. These adaptive signal models are obtained by using different approaches so as to extract a multi-part model from the audio signal. The(More)
The ISO-MPEG standards are widely used for high quality audio coding. They use perceptual models that require high frequency resolution. This implies two characteristics: they use high selectivity filter bank to decompose the audio signal, and the FFT frame length for the frequency masking threshold calculations is long. Both characteristics carried out a(More)
This paper outlines a wavelet based audio coding scheme that uses a perceptual entropy criterion to achieve a signal adapted wavelet tree. We are interested in decompositions adapted to the nature of audio signals, but attending to the characteristics of the human hearing system. Our audio coder is compared with two other wavelet based coding schemes: the(More)
The inhibition of the specific R-[3H]-baclofen binding to GABAB (gamma-aminobutyric acid) sites by a homologous series of phenyl alcohol amides was tested in rat brain synaptic membranes. Some of these phenyl alcohol amides were designed as anticonvulsants as well as antagonists of the GABAB receptor. These anticonvulsants showed a high affinity to the(More)
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