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Research that is initiated, designed or funded by sponsor agencies based in countries with relatively high social and economic development, and conducted in countries that are relatively less developed, gives rise to many important ethical challenges. Although clinical trials of HIV vaccines began ten years ago in the US and Europe, an increasing number of(More)
OBJECTIVES Aboriginal Canadians (i.e., First Nations, Inuit and Métis) are disproportionately affected by HIV/AIDS, and experience greater social and economic marginalization and poorer housing conditions. This study sought to understand the differences in the determinants of health and housing-related characteristics between samples of Aboriginal and(More)
BACKGROUND Social determinants of health (SDOH) may influence the probability of people living with HIV also being infected with hepatitis C virus (HCV). We compared the SDOH of adults co-infected with HCV/HIV with that of HIV mono-infected adults to identify factors independently associated with HCV infection. METHODS In this cross-sectional study,(More)
Despite the importance of sustained use of healthcare information systems, research on the continuous use of these systems is scanty, especially for clinical decision support systems. Moreover, there is an apparent gap between information systems and healthcare research approaches in studying use. We address these gaps by creating a comprehensive model(More)
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