Dale A. Schoeller

Jacob Plange-Rhule6
Pascal Bovet6
Amy Luke6
Lara R Dugas3
Estelle V Lambert3
6Jacob Plange-Rhule
6Pascal Bovet
6Amy Luke
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BACKGROUND Short sleep is associated with obesity and may alter the endocrine regulation of hunger and appetite. OBJECTIVE We tested the hypothesis that the curtailment of human sleep could promote excessive energy intake. DESIGN Eleven healthy volunteers [5 women, 6 men; mean +/- SD age: 39 +/- 5 y; mean +/- SD body mass index (in kg/m(2)): 26.5 +/-(More)
We describe the approach taken by the National Children's Study (NCS) to understanding the role of environmental factors in the development of obesity. We review the literature with regard to the two core hypotheses in the NCS that relate to environmental origins of obesity and describe strategies that will be used to test each hypothesis. Although it is(More)
BACKGROUND Populations in transition to a Western lifestyle display increased incidences of obesity, type 2 diabetes, and other chronic diseases; the mechanisms responsible for these changes, however, remain incompletely understood. Although reduced physical activity has been implicated, few studies have accurately quantified energy expenditure in(More)
BACKGROUND While the preclinical development of type 2 diabetes is partly explained by obesity and central adiposity, psychosocial research has shown that chronic stressors such as discrimination have health consequences as well. PURPOSE We investigated the extent to which the well-established effects of obesity and central adiposity on nondiabetic(More)
OBJECTIVE Obesity and diabetes are characterized by the incapacity to use fat as fuel. We hypothesized that this reduced fat oxidation is secondary to a sedentary lifestyle. RESEARCH DESIGN AND METHODS We investigated the effect of a 2-month bed rest on the dietary oleate and palmitate trafficking in lean women (control group, n = 8) and the effect of(More)
BACKGROUND Skeletal muscle tissue holds a large volume of water partitioned into extracellular water (ECW) and intracellular water (ICW) fractions. As the ECW may not be related to muscle strength directly, we hypothesized that excluding ECW from muscle volume would strengthen the correlation with muscle strength. METHODS A total of 119 healthy men aged(More)
OBJECTIVES Changes in the way dietary fat is metabolized can be considered causative in obesity. The role of sedentary behavior in this defect has not been determined. We hypothesized that physical inactivity partitions dietary fats toward storage and that a resistance exercise training program mitigates storage. DESIGN We used bed rest, with(More)
BACKGROUND Examination of patterns and intensity of physical activity (PA) across cultures where obesity prevalence varies widely provides insight into one aspect of the ongoing epidemiologic transition. The primary hypothesis being addressed is whether low levels of PA are associated with excess weight and adiposity. METHODS We recruited young adults(More)
A 12-week randomized controlled multi-center clinical trial was conducted in 106 overweight and obese adults. Diets were designed to produce a 2,093 kJ/day energy deficit with either low calcium (LC; ~600 mg/day), high calcium (HC; ~1,400 mg/day), or high dairy (HD; three dairy servings, diet totaling ~1,400 mg/day). Ninety-three subjects completed the(More)
  • Herman Pontzer, Ramon Durazo-Arvizu, Lara R Dugas, Jacob Plange-Rhule, Pascal Bovet, Terrence E Forrester +4 others
  • 2016
Current obesity prevention strategies recommend increasing daily physical activity, assuming that increased activity will lead to corresponding increases in total energy expenditure and prevent or reverse energy imbalance and weight gain [1-3]. Such Additive total energy expenditure models are supported by exercise intervention and accelerometry studies(More)