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Development of an autophagy-related gene expression signature for prognosis prediction in prostate cancer patients
TLDR
The authors' ARGs based prediction models are a reliable prognostic and predictive tool for overall survival and disease-free survival in prostate cancer patients. Expand
Risk factors of lateral lymph node metastasis in cN0 papillary thyroid carcinoma
TLDR
Large tumor size, tumor located in the upper lobe, multifocality, extrathyroidal extension, and ≥ 2 CLN metastases may increase the risk of LLN metastasis in cN0 PTC patients. Expand
Deciphering N6-Methyladenosine-Related Genes Signature to Predict Survival in Lung Adenocarcinoma
TLDR
A m6A-based signature to predict the overall survival (OS) in LUAD was successfully established, and it was found that most of the m 6A-related genes were differentially expressed between tumor and non-tumor tissues. Expand
Individualized Prediction Of Metastatic Involvement Of Lymph Nodes Posterior To The Right Recurrent Laryngeal Nerve In Papillary Thyroid Carcinoma
TLDR
The risk of LN-prRLN metastasis in individual patients can be robustly predicted by a nomogram that integrates readily available preoperative clinicopathologic features and intraoperative frozen section examination and may facilitate intraoperative decision-making for patients with PTC. Expand
Co-existence of BRAFV600E and TERT promoter mutations in papillary thyroid carcinoma is associated with tumor aggressiveness, but not with lymph node metastasis
TLDR
It was demonstrated that the coexistence of BRAF and TERT promoter mutations were associated with the PTC aggressiveness, although these mutations were not associated with PTC lymph node metastasis or with PTMC. Expand
NPRL2 promotes docetaxel chemoresistance in castration resistant prostate cancer cells by regulating autophagy through the mTOR pathway.
TLDR
Investigation of the role of NPRL2 in the chemoresistant CRPC cells found thatNPRL2 was significantly overexpressed in docetaxel-resistantCRPC cells, while autophagy was enhanced and mTOR signaling was inhibited. Expand
Development of an autophagy-related gene prognostic signature in lung adenocarcinoma and lung squamous cell carcinoma
TLDR
The prognostic signature which contains six autophagy-related genes showed good performance for predicting the survival of LUAD and LUSC patients by having a better Area Under Curves (AUC) than other clinical parameters. Expand
Identification of Prognostic Immune-Related Genes by Integrating mRNA Expression and Methylation in Lung Adenocarcinoma
TLDR
It is demonstrated that high-risk patients had significantly shorter overall survival (OS) than low- risk patients, and methylation levels of INHA, S100A16, the CpG site cg23851011, and the cg06552037 are promising biomarkers for monitoring the outcomes of LUAD. Expand
Multi-gene assay and clinical characteristics research in papillary thyroid carcinoma.
TLDR
BRAF V600E mutation was associated with older age and the aggressiveness of PTC but was independent of lymph node metastasis (LNM), and RET/PTC rearrangement suggested more LNM in young patients with PTC. Expand
Database Mining of Genes of Prognostic Value for the Prostate Adenocarcinoma Microenvironment Using the Cancer Gene Atlas
TLDR
A list of genes associated with the prostate adenocarcinoma microenvironment, which might contribute to the prediction and interpretation of PRAD prognosis are extracted. Expand
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