Daisy Castro

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OBJECTIVE To describe the clinical and pathological features of patients with retinoblastoma and microscopic scleral invasion. METHODS We reviewed all pathology slides of patients with microscopic scleral invasion who were included in 3 prospective treatment protocols (1988-2007). All patients received adjuvant chemotherapy (moderately intensive(More)
OBJECTIVE To investigate the safety and efficacy of alloantigen plasmid DNA therapy in patients with advanced head and neck squamous cell carcinoma using Allovectin-7 (Vical Inc, San Diego, Calif), a DNA/lipid complex designed to express the class I major histocompatibility complex antigen HLA-B7. DESIGN Multi-institutional prospective trial. SETTING(More)
Intratumoral injections of cisplatin/epinephrine-injectable gel were administered weekly for 4 weeks in 45 patients with malignant tumors of various histologic types. Tumors were located on the skin and subcutaneous tissue primarily of the head, neck, and trunk, and on the tongue, oral pharynx, and esophagus. Patients were not candidates for surgery,(More)
OBJECTIVES To study the role of IL-12p40 at the onset of reactive arthritis (ReA) after Yersinia enterocolitica O:3 infection, and analyse relevant microbial antigens and articular expression of Toll-like receptor (TLR) mRNA. METHODS Wild-type C57BL/6 and IL-12p40-deficient (IL-12p40-/-) mice were orogastrically infected with Y. enterocolitica O:3. Early(More)
PURPOSE To evaluate the feasibility, efficacy and safety of the use of 4F Judkins catheters for coronary angiography. METHODS From August/95 to January/96, 70 patients with suspected coronary artery disease underwent coronary cineangiography by the Judkins technique, with 4F catheters. Following puncture of the right femoral artery, 4F sheaths were(More)
Current investigations deal with new surface functionalization strategy of nanocrystalline cellulose-based substrates to impart active molecule release properties. In this study, cellulose nanocrystals (CNC) were surface-functionalized with β-cyclodextrin (β-CD) using succinic acid (SA) and fumaric acid (FA) as bridging agents. The main objective of this(More)
Red blood cell counts, haemoglobin, haematocrit, MCV, MCH, MCHC, RDW, platelet count, plateletcrit, platelet distribution width, white blood cell count, white cell differential count (absolute and per cent) and serum iron were studied in 167 people (96 women and 71 men) aged between 60 and 89 years. Significant differences between both sexes were found for(More)
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