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  • Takumi Ota, Masao Doi, +7 authors Hitoshi Okamura
  • Biology, Medicine
  • Molecular and cellular biology
  • 15 October 2014
  • The 3β-hydroxysteroid dehydrogenase (3β-HSD) is an enzyme crucial for steroid synthesis. Two different 3β-HSD isoforms exist in humans. Classically, HSD3B2 was considered the principal isoformContinue Reading
  • Daisuke Yarimizu, Masao Doi, Takumi Ota, Hitoshi Okamura
  • Medicine
  • Endocrine journal
  • 2015
  • In the adrenal, the type I 3β-hydroxysteroid dehydrogenase (HSD3B1) is expressed exclusively in the zona glomerulosa (ZG), where aldosterone is produced. Angiotensin II (AngII) and potassium (K(+))Continue Reading