Daisuke Tamura

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In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses

Yasushi Itoh, Kyoko Shinya, +49 authors Yoshihiro Kawaoka
Nature
2009

Influenza A viruses cause recurrent outbreaks at local or global scale with potentially severe consequences for human health and the global economy. Recently, a new strain of influenza A virus was… (More)

Sorafenib inhibits the hepatocyte growth factor-mediated epithelial mesenchymal transition in hepatocellular carcinoma.

Tomoyuki Nagai, Tokuzo Arao, +11 authors Kazuto Nishio
Molecular cancer therapeutics
2011

The epithelial mesenchymal transition (EMT) has emerged as a pivotal event in the development of the invasive and metastatic potentials of cancer progression. Sorafenib, a VEGFR inhibitor with… (More)

FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth.

Hiroyasu Kaneda, Tokuzo Arao, +12 authors Kazuto Nishio
Cancer research
2010

Forkhead box Q1 (FOXQ1) is a member of the forkhead transcription factor family, and it has recently been proposed to participate in gastric acid secretion and mucin gene expression in mice. However,… (More)

Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model.

Toru Hiraga, Paul J Williams, Akimi Ueda, Daisuke Tamura, T. Yoneda
Clinical cancer research : an official journal of…
2004

PURPOSE It is established that bisphosphonates (BPs), specific inhibitors of osteoclasts, have beneficial effects on bone metastases of breast cancer. In addition, recent studies have reported that… (More)

mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells.

Kazuko Matsumoto, Tokuzo Arao, +9 authors Kazuto Nishio
Cancer research
2009

The underlying mechanism regulating the expression of the cancer stem cell/tumor-initiating cell marker CD133/prominin-1 in cancer cells remains largely unclear, although knowledge of this mechanism… (More)

C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis.

Akira Myoui, Riko Nishimura, +5 authors T. Yoneda
Cancer research
2003

The proto-oncogene, c-src, has been implicated in the tumorigenesis in breast cancer. However, the relationship of c-src with distant metastasis is unclear. Moreover, the role of c-src in… (More)

Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone.

Daisuke Tamura, Toru Hiraga, Akira Myoui, Hideki Yoshikawa, T. Yoneda
International journal of oncology
2008

Cell adhesion molecules have been implicated in the selective colonization of cancer in distant organs. Breast cancer has a strong predilection for spreading to bone. Cadherin-11, which is one of the… (More)

Prognostic relevance of clinical symptoms in patients with spinal metastases.

Noboru Hosono, Takafumi Ueda, Daisuke Tamura, Yasuaki Aoki, Hideki Yoshikawa
Clinical orthopaedics and related research
2005

UNLABELLED Medical and surgical advances allow surgical treatment of many patients with spinal metastases. Although emerging surgical techniques facilitate stabilization of the collapsed spine,… (More)

Cell culture-selected substitutions in influenza A(H3N2) neuraminidase affect drug susceptibility assessment.

Daisuke Tamura, Ha T. Nguyen, +8 authors Larisa V. Gubareva
Antimicrobial agents and chemotherapy
2013

Assessment of drug susceptibility has become an integral part of influenza virus surveillance. In this study, we describe the drug resistance profile of influenza A(H3N2) virus,… (More)

Significance of seasonal influenza viruses in the stool of pediatric patients.

Daisuke Tamura, Motoko Fujino, +6 authors Yoshihiro Kawaoka
The Pediatric infectious disease journal
2010

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