Daisuke Hihara

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During mitosis, the spindle assembly checkpoint (SAC) inhibits the Cdc20-activated anaphase-promoting complex/cyclosome (APC/C(Cdc20)), which promotes protein degradation, and delays anaphase onset to ensure accurate chromosome segregation. However, the SAC function in meiotic anaphase regulation is poorly understood. Here, we examined the SAC function in(More)
Ultrathin colonoscopes (UTC) reportedly produce less pain during colonoscopy than standard colonoscopes. The aim of this study was to assess the tolerability of an UTC compared with that of a pediatric colonoscope. A total of 270 adult patients scheduled to undergo colonoscopy were randomized, with 134 allocated to the UTC group and 136 to the pediatric(More)
The Rockefeller University Press $30.00 J. Cell Biol. Vol. 182 No. 2 277–288 www.jcb.org/cgi/doi/10.1083/jcb.200802053 JCB 277 Correspondence to Ayuma Yamamoto: sayamam@ipc.shizuoka.ac.jp Abbreviations used in this paper: APC/C, anaphase promoting complex/cyclosome; MI, meiosis I; MII, meiosis II; SAC, spindle assembly checkpoint; SPB, spindle pole body.(More)
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