Daisuke Fukuda

Learn More
BACKGROUND Understanding how complex antibiotics are synthesised by their producer bacteria is essential for creation of new families of bioactive compounds. Thiomarinols, produced by marine bacteria belonging to the genus Pseudoalteromonas, are hybrids of two independently active species: the pseudomonic acid mixture, mupirocin, which is used clinically(More)
In acidic forest soils, microorganisms should adapt to toxicity of aluminum (Al), which is solubilized by acidity. We hypothesized that Al-resistant bacteria are diverse, especially in soils with high levels of Al, because these bacteria are expected to have adapted to Al stress over a long time. We isolated Al-resistant bacteria from acid forest soils(More)
Helicobacter pylori infection is the most common infectious disease worldwide and is thought to be a cause of gastric cancer [Park et al. 2014]. Standard therapy against H. pylori infection comprises co-administration of a proton-pump inhibitor with antibiotics; however, maintaining the pH of the stomach mucosa to preserve antibiotic function can be(More)
SUMMARY As the technology of VLSI manufacturing process continues to shrink, it becomes a challenging problem to generate layout patterns that can satisfy performance and manufacturability requirements. Wire width variation is one of the main issues that have a large impact on chip performance and yield loss. Particularly, etching process is the last and(More)
SUMMARY As VLSI process node continue to shrink, chemical mechanical planarization (CMP) process for copper interconnect has become an essential technique for enabling many-layer interconnection. Recently, Edge-over-Erosion error (EoE-error), which originates from overpolishing and could cause yield loss, is observed in various CMP processes, while its(More)
  • 1