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The validity of the Child Feeding Questionnaire (CFQ), one of the measures used to assess parental child feeding practices and attitudes, has been confirmed in American populations. We used confirmatory factor analysis to test the validity and factor structure of the translated version of the CFQ among parents of Japanese elementary school children. The(More)
OBJECTIVES This study examines the gender differences in the association between maternal smoking during pregnancy and later growth in childhood. DESIGN Ongoing prospective cohort study, which is called 'the Project Koshu', initiated in the foetal stage to the age of 9-10 years. SETTING Koshu City which was in Japanese rural area. PARTICIPANTS The(More)
BACKGROUND Although maternal smoking during pregnancy has been reported to have an effect on childhood overweight/obesity, the impact of maternal smoking on the trajectory of the body mass of their offspring is not very clear. Previously, we investigated this effect by using a fixed-effect model. However, this analysis was limited because it rounded and(More)
Sjögren's syndrome is a human autoimmune disease characterized by lymphocytic infiltration of salivary and lacrimal glands, hypergammaglobulinemia, and specific autoantibodies. The accessibility of the salivary gland to biopsy provides an opportunity to study cytokine mRNA expression at the site of organ-specific immune damage. Using reverse transcriptase(More)
The vasa genes are expressed in the germ cell lineage in many organisms, but their expression patterns show large variations. Recent studies suggest that vasa transcripts are involved in germ cell lineage development. In this paper, we isolated the vasa cDNA clone from a teleost, shiro-uo, Leucopsarion petersii and examined its expression pattern during(More)
We investigated the relation between the vitamin D receptor (VDR) genotype and bone mass including the effect of exercise history as a measure of physical activity. BUA (broadband ultrasound attenuation), SOS (speed of sound) and Stiffness index of the calcaneus were measured using an ultrasound bone densitometer in 105 Japanese young adult women (age:(More)
Irisin is mainly released from skeletal muscle (myocytes) and promotes thermogenesis by browning of the white adipose tissue. Although exercise has been shown to increase irisin concentration in blood and myocytes via up-regulation peroxisome proliferator receptor γ coactivator-1α (PGC-1α) expression, the influence of exercise intensity on irisin secretion(More)
BACKGROUND We previously reported that a number of factors related to maternal lifestyle during early pregnancy, including smoking, are associated with childhood obesity at 5 years of age. In the present study, we investigated whether the association with maternal smoking persisted to the age of 9-10 years. METHODS The study population comprised children(More)
OBJECTIVE We determined detailed time-course changes in the irisin response to acute exercise using different exercise modes. METHODS In experiment 1, seven healthy males rested for 12h (8:00-20:00) to determine the diurnal variation in plasma irisin concentration. In experiment 2, 10 healthy males conducted three exercises to clarify time-course changes(More)
PURPOSE To assess whether genetic polymorphisms of the apolipoprotein E (APOE) gene are associated with open angle glaucoma (OAG) in the Japanese population. METHODS Genomic DNA was examined in a cohort of 310 Japanese patients with OAG and 179 control subjects. The average age was 63.5+/-14.4 years (mean+/-SD) for the OAG patients and 65.5+/-11.6 years(More)