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BACKGROUND Data on acid and non-acid reflux patterns and esophageal function in Japanese patients with non-erosive reflux disease (NERD) are limited. The aim of this study was to use combined(More)
BACKGROUND Early induction with biologics can reduce complications in patients with Crohn's disease (CD) and improve their quality of life. The safety of biologics, however, is uncertain. Granulocyte(More)
CONTEXT Plasma liver-specific mRNAs are useful biomarkers of hepatotoxicity in rats. OBJECTIVE To investigate the potential application of liver-specific mRNAs as biomarkers for liver injury in(More)
Whether or not the eradication of Helicobacter pylori is a risk factor for reflux esophagitis (RE) is a question at issue. To find an answer, it is necessary to clarify the influence of H. pylori(More)
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