Learn More
INTRODUCTION There is strong evidence that high meat intake increases the risk of colorectal cancer. However, for other cancer sites there is currently less convincing evidence. METHODS To further explore associations between meat intake and cancer risk we conducted a multisite case-control study of 11 cancer sites in Uruguay between 1996 and 2004,(More)
BACKGROUND The association between intake of dairy products and the risk of type 2 diabetes has been investigated in several studies, but the evidence is not conclusive. OBJECTIVE We conducted an updated systematic review and dose-response meta-analysis of dairy product intake and the risk of type 2 diabetes. DESIGN We searched the PubMed database for(More)
BACKGROUND The evidence that red and processed meat influences colorectal carcinogenesis was judged convincing in the 2007 World Cancer Research Fund/American Institute of Cancer Research report. Since then, ten prospective studies have published new results. Here we update the evidence from prospective studies and explore whether there is a non-linear(More)
A multisite case-control study on factor analysis and several cancer sites (mouth and pharynx, esophagus, stomach, colon, rectum, larynx, lung, breast, prostate, bladder, kidney) was conducted in Uruguay. The study included 3,528 cases and 2,532 controls. Factor analysis (principal components) was modeled among controls. This patterning method retained 4(More)
OBJECTIVE To investigate the association between intake of dietary fibre and whole grains and risk of colorectal cancer. DESIGN Systematic review and meta-analysis of prospective observational studies. DATA SOURCES PubMed and several other databases up to December 2010 and the reference lists of studies included in the analysis as well as those listed(More)
BACKGROUND Questions remain about the shape of the dose-response relationship between body mass index (BMI) and pancreatic cancer risk, possible confounding by smoking, and differences by gender or geographic location. Whether abdominal obesity increases risk is unclear. METHODS We conducted a systematic review and meta-analysis of prospective studies of(More)
In order to explore the role of broader eating patterns in the etiology of prostate cancer, we conducted a principal components analysis among Uruguayan men. The study included 345 newly diagnosed cases of advanced prostate cancer and 690 hospitalized controls. The factor analysis was performed using the control population. Factor analysis allowed the(More)
BACKGROUND There is limited, but inconclusive, epidemiological evidence that high folate intake decreases the risk of colorectal and esophageal cancers. For other cancer sites, the evidence is even less consistent or extensive. MATERIALS AND METHODS We conducted a case-control study of dietary folate intake and risk of 11 cancer sites in Uruguay between(More)
INTRODUCTION Previous studies have suggested that high intake of fruit and vegetables may decrease the risk of a wide range of cancers, but this evidence has been challenged by the results of recent studies. METHODS To further explore the association between fruit and vegetable intake and cancer risk we conducted a case-control study of 11 cancer sites in(More)
BACKGROUND Positive association between obesity and survival after breast cancer was demonstrated in previous meta-analyses of published data, but only the results for the comparison of obese versus non-obese was summarised. METHODS We systematically searched in MEDLINE and EMBASE for follow-up studies of breast cancer survivors with body mass index (BMI)(More)