Dafydd J Thomas

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Asymptomatic internal carotid artery stenosis and cerebrovascular risk stratification.

Andrew Nicolaides, Stavros K. Kakkos, +10 authors Anne Abbott
Journal of vascular surgery
2010

BACKGROUND The purpose of this study was to determine the cerebrovascular risk stratification potential of baseline degree of stenosis, clinical features, and ultrasonic plaque characteristics in… (More)

Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples

Andrew F. Hill, R. J. Butterworth, +12 authors John Collinge
The Lancet
1999

BACKGROUND Prion diseases are associated with the accumulation of an abnormal isoform of cellular prion protein (PrPSc), which is the principal constituent of prions. Prions replicate in… (More)

10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial

Alison W. Halliday, Michael J. G. Harrison, +11 authors Dafydd J Thomas
The Lancet
2010

BACKGROUND If carotid artery narrowing remains asymptomatic (ie, has caused no recent stroke or other neurological symptoms), successful carotid endarterectomy (CEA) reduces stroke incidence for some… (More)

Markers of endothelial dysfunction in lacunar infarction and ischaemic leukoaraiosis.

Ahamad Hassan, Beverley J Hunt, +6 authors Hugh S. Markus
Brain : a journal of neurology
2003

Patients with cerebral small vessel disease (SVD) can present as isolated lacunar infarction or with diffuse white matter changes, with the imaging appearance of leukoaraiosis. Endothelial… (More)

Kuru in the 21st century—an acquired human prion disease with very long incubation periods

John Collinge, Jerome Whitfield, +4 authors Michael P. Alpers
The Lancet
2006

BACKGROUND Kuru provides the principal experience of epidemic human prion disease. Its incidence has steadily fallen after the abrupt cessation of its route of transmission (endocannibalism) in Papua… (More)

Effect of haematocrit on cerebral blood-flow in man.

Dafydd J Thomas, John Marshall, +5 authors Elias Zilkha
Lancet
1977

Cerebral blood-flow (C.B.F.) was measured in 38 patients with haematocrit values (Hct) in the range 0-47--0-53 and was found to be significantly lower than in 43 patients with Hct in a lower range… (More)

Clinical NMR imaging of the brain: 140 cases.

Graeme M. Bydder, Robert E. Steiner, +5 authors Nigel J. Legg
AJR. American journal of roentgenology
1982

Cranial nuclear magnetic resonance (NMR) scans were performed on 13 healthy volunteers and 140 patients with a broad spectrum of neurologic disease and compared with x-ray computed tomography (CT)… (More)

Brain dehydration and neurologic deterioration after rapid correction of hyponatremia.

Richard H. Sterns, Dafydd J Thomas, Robert M. Herndon
Kidney international
1989

We made rats severely hyponatremic, varying the rate of onset and duration of the disturbance, and then compared rapid correction to slow correction. An acute fall in the plasma Na to 106 mEq/liter… (More)

The size of juxtaluminal hypoechoic area in ultrasound images of asymptomatic carotid plaques predicts the occurrence of stroke.

Stavros K. Kakkos, Maura B Griffin, +6 authors George Geroulakos
Journal of vascular surgery
2013

OBJECTIVE To test the hypothesis that the size of a juxtaluminal black (hypoechoic) area (JBA) in ultrasound images of asymptomatic carotid artery plaques predicts future ipsilateral ischemic stroke.… (More)

Biomechanics of Skull Fracture

Narayan Yoganandan, Frank A. Pintar, +4 authors R. Garfield Snyder
Journal of neurotrauma
1995

This study was conducted to determine the biomechanics of the human head under quasistatic and dynamic loads. Twelve unembalmed intact human cadaver heads were tested to failure using an… (More)

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