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INTRODUCTION: First-pass cardiac perfusion MRI requires fast data acquisition to achieve an appropriate combination of temporal resolution, spatial resolution and spatial coverage for clinical studies [1]. We have recently presented a combination of compressed sensing and parallel imaging (k-t SPARSE-SENSE) to highly accelerate perfusion studies by jointly(More)
Breath-held, accelerated 3D first-pass perfusion images of a healthy volunteer: (top rows) CS-PI-PF (R=24) and (bottom rows) TGRAPPA (R=8). Myocardial contours are zoomed in 4 th partition in the right side, as indicated by the red boxes. Fig. 1: k y-k z-t sampling pattern with R=24 using a combination of different random undersampling patterns for each(More)
PURPOSE To demonstrate the phase evolutions of direct visualization of short transverse relaxation time component (ViSTa) matches with those of myelin water. METHOD Myelin water imaging (MWI) measures short transverse signals and has been suggested as a biomarker for myelin. Recently, a new approach, ViSTa, has been proposed to acquire short T2* signals(More)
Glucocorticoids are associated with obesity, but the underlying mechanism by which they function remains poorly understood. Previously, we showed that small G protein Dexras1 is expressed by glucocorticoids and leads to adipocyte differentiation. In this study, we explored the mechanism by which Dexras1 mediates adipogenesis and show a link to the(More)
A organocatalytic system based on economical and readily available cyanuric acid has been developed for the synthesis of 2-oxazolidinones and quinazoline-2,4(1H,3H)-diones from propargylamines and 2-aminobenzonitriles under atmospheric pressure carbon dioxide. Notably, a low concentration of carbon dioxide in air was directly converted into 2-oxazolidinone(More)
This work proposes a family of greedy algorithms to jointly reconstruct a set of vectors that are (i) nonnegative and (ii) simultaneously sparse with a shared support set. The proposed algorithms generalize previous approaches that were designed to impose these constraints individually. Similar to previous greedy algorithms for sparse recovery, the proposed(More)
PURPOSE To propose and evaluate a novel multidimensional approach for imaging subvoxel tissue compartments called Diffusion-Relaxation Correlation Spectroscopic Imaging. THEORY AND METHODS Multiexponential modeling of MR diffusion or relaxation data is commonly used to infer the many different microscopic tissue compartments that contribute signal to(More)
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