Dae hyun Lew

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BACKGROUND Numerous processing methods have been proposed to enhance the survival of fat grafts, but no definitive treatment protocol is available. Platelet-rich plasma (PRP) contains a high concentration of platelets with neovascularization properties and has the potential to promote fat graft survival. OBJECTIVE To evaluate the effect of activated PRP(More)
BACKGROUND Adipose-derived stem cells (ASCs) have positive effects in the wound healing process. OBJECTIVE To clarify whether ASCs positively mitigate scar formation in the wound remodeling process. MATERIALS AND METHODS Full-thickness skin defects were created on the dorsal skin of Yorkshire pigs. After the defects were transformed into early scars,(More)
BACKGROUND Robots have allowed head and neck surgeons to extirpate oropharyngeal tumors safely without the need for lip-split incision or mandibulotomy. Using robots in oropharyngeal reconstruction is new but essential for oropharyngeal defects that result from robotic tumor excision. We report our experience with robotic free-flap reconstruction of head(More)
BACKGROUND AIMS Adipose-derived stem cells (ASC) are known to be able to restore injured tissue via differentiation and paracrine effects. In this study, we investigated the effect of ASC on photo-aged human dermal fibroblasts (HDF) based on paracrine function. In particular, we wanted to determine a more effective method of ASC application and the fate of(More)
Hydroxyapatite cement is an ideal alloplastic material to replace the autogenous bone grafts in craniofacial surgery. Hydroxyapatite cement is advantageous because it can be easily molded by hand unlike other alloplastic materials such as silicone and high-density polyethylene. For aesthetic applications of hydroxyapatite cement, we evaluated the efficacy(More)
Improvement of flap survival represents an ongoing challenge in reconstructive surgery. The angiogenic potential of adipose-derived stem cells (ASCs) offers a promising approach to improve the viability of random pattern flaps. Recently, to maximize the therapeutic effects of ASCs, increasing focus is being placed on how to deliver the stem cells to target(More)
BACKGROUND Reduction malarplasty to correct prominent malar complex is popular in Asians. Despite the popularity of reduction malarplasty, most of the surgical methods applied are not selected according to the degree of zygoma protrusion. In this study, we analyzed the effectiveness of two different surgical procedures to clarify their appropriateness for(More)
BACKGROUND Composite grafts are suitable for facial reconstruction because of good color matching, low donor-site morbidity, acceptable texture, and easy surgical techniques. However, their use is limited to small defects and by unpredictable survival rates. As platelet-rich plasma contains large numbers of growth factors and has been widely used for tissue(More)
BACKGROUND For patients with full thickness skin defects, autologous Split-thickness skin grafts (STSG) are generally regarded as the mainstay of treatment. However, skin grafts have some limitations, including undesirable outcomes resulting from scars, poor elasticity, and limitations in joint movement due to contractures. In this study, we present(More)
PURPOSE The objective of this study was to evaluate the course of healing of craniofacial bone defects when filled with hydroxyapatite cement and to determine whether adding various percentages by weight of demineralized bone powder to the cement will result in enhanced bone formation. MATERIALS AND METHODS The model for the study was the canine(More)