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Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells.
- Dae-Seop Shin, Hye-Nan Kim, B. Kwon
- Biology, ChemistryCancer research
- 2009
TLDR
KRIBB11 Inhibits HSP70 Synthesis through Inhibition of Heat Shock Factor 1 Function by Impairing the Recruitment of Positive Transcription Elongation Factor b to the hsp70 Promoter*
- Y. Yoon, Joo Ae Kim, D. Han
- BiologyThe Journal of Biological Chemistry
- 15 November 2010
TLDR
Blocking Tumor Cell Migration and Invasion with Biphenyl Isoxazole Derivative KRIBB3, a Synthetic Molecule That Inhibits Hsp27 Phosphorylation*
- Ki Deok Shin, Mi-Young Lee, D. Han
- Biology, ChemistryJournal of Biological Chemistry
- 16 December 2005
TLDR
Predicted drug-induced bradycardia related cardio toxicity using a zebrafish in vivo model is highly correlated with results from in vitro tests.
- M. Park, Kyeong-Ryoon Lee, M. Bae
- Biology, MedicineToxicology letters
- 10 January 2013
Phosphatase of regenerating liver‐3 promotes migration and invasion by upregulating matrix metalloproteinases‐7 in human colorectal cancer cells
- Su‐Kyung Lee, Young-Min Han, B. Kwon
- BiologyInternational journal of cancer
- 1 August 2012
TLDR
Apoptosis induction of 2'-hydroxycinnamaldehyde as a proteasome inhibitor is associated with ER stress and mitochondrial perturbation in cancer cells.
- Su-Hyung Hong, Jina Kim, B. Kwon
- Biology, ChemistryBiochemical pharmacology
- 15 August 2007
Sugiol inhibits STAT3 activity via regulation of transketolase and ROS-mediated ERK activation in DU145 prostate carcinoma cells.
- Seung-Nam Jung, Dae-Seop Shin, B. Kwon
- Biology, ChemistryBiochemical pharmacology
- 1 September 2015
Computational determination of hERG-related cardiotoxicity of drug candidates
- Hyang-Mi Lee, Myeong-Sang Yu, D. Na
- Biology, MedicineBMC Bioinformatics
- 29 May 2019
TLDR
Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed rat2 cells and induces apoptosis through caspase-3 pathway.
- Hyun-Mi Kang, Su‐Kyung Lee, B. Kwon
- Biology, ChemistryLife sciences
- 2 January 2006
Synthesis and biological evaluation of dimeric cinnamaldehydes as potent antitumor agents.
- Dae-Seop Shin, Jong-Han Kim, B. Kwon
- Chemistry, BiologyBioorganic & medicinal chemistry
- 15 April 2006
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