Dae-Seok Han

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AIM OF THE STUDY Many medicinal plants have been used for treatment of insomnia in Asia. However, scientific evidence and precise mechanism for their sedative-hypnotic activity have not been fully investigated. Thus, we investigated the binding activity of the oriental plant extracts (mainly from Korea and Japan) to the well-known molecular targets for(More)
Purpose Bromelain, a pineapple extract, is a complex mixture of proteases and protease inhibitors. Although bromelain (Br) has been used clinically for over 40 years, the active constituents that mediate its anti-inflammatory activity are not thoroughly characterized and no biomarker exists to evaluate absorbed peptides and their potential therapeutic(More)
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