DMSc O. H. Nielsen MD

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The pathogenetic role of activated αβ and γδ T cells in inflammatory bowel disease (IBD) is not well defined. To elucidate this, interluekin-2 receptor (IL-2R) α and IL-2Rβ single chain expression and coexpression by peripheral blood TCRαβ+ cells and TCRγδ+ cells was studied in 21 patients with ulcerative colitis (UC), 25 with Crohn's disease (CD), and 15(More)
The adhesion molecule, lymphocyte function associated antigen 1 (LFA-1) consisting of two subunits, CD11a and CD18, mediates lymphocyte migration into tissue and cell effector functions. Previous observations showed no differences in LFA-1 expression by circulating lymphocytes between inflammatory bowel disease patients and controls. The aim of the present(More)
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