DM Lillington

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The clinical, haematological and cytogenetic data for 20 patients with an acquired abnormality of 11q23 and 10p have been reviewed at this workshop. Patients predominantly presented with de novo AML M5a and the most common cytogenetic finding was an inversion of part of the long arm of chromosome 11 followed by a translocation between 11q and 10p. Band p12(More)
Thirty patients representing 5.5% of those collected by the 11q23 workshop had a t(6;11)(q27;q23). They included 27 cases of acute myeloid leukemia (AML) (M1, three cases; M2, two cases; M4, nine cases; M4/M5, one case; M5, 12 cases) of age range 3–72 years and three cases of acute lymphoblastic leukemia (ALL) (B-lineage ALL, two cases; T-ALL, one case) of(More)
Between october 1993 and march 1999, 29 patients with cml who were ineligible for allogeneic bmt underwent pbsc harvest using idarubicin, cytarabine and g-csf. in 9/29 (31%) patients all collected stem cells were ph-negative, and 15/29 patients’ (52%) collections were substantially (>95%) Ph-negative. The proportion of patients from whom Ph-negative stem(More)
1a 3/F 19.4 pre-B cell 111+ 146,XX,t(8;14)(q11.2;q32), t(9;22)(q34;q11) 46,XX,t(9;22)(q34;q11) 348,XX,t(9;22)(q34;q11),+21,+der(22)t(9;22)(q34;q11)/ 48,idem,t(1;3)(q32;q27)/48,idem,t(1;4)(p36;q31) 2 9/M 6.4 pre-B cell 8+ 146,XY,t(8;14)(q11;q32), del(18)(p11.2p11.3),der(19)t(8;19)(?;p13).ish t(8;14)(wcp8+,IGH5’+;wcp14+,IGH3’+,wcp8+), der(19)(wcp8+;wcp19+) 3(More)
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