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Most cases of breast cancer (BrCa) mortality are due to vascular metastasis. BrCa cells must intravasate through endothelial cells (ECs) to enter a blood vessel in the primary tumor and then adhere to ECs and extravasate at the metastatic site. In this study we demonstrate that inhibition of hypoxia-inducible factor (HIF) activity in BrCa cells by RNA(More)
Public Health agencies need up-to-date population data, and Statistics Canada's Taxation Family File (T1FF) database, developed annually from T1 personal income tax forms, may meet this need. We compared 1989 T1FF data for Ottawa-Carleton with census data. The overall population estimate for the region was 98% of the census figure. Equivalent figures were(More)
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