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The healing process in full-thickness skin wounds includes coagulation, inflammation, tissue formation, and tissue remodeling [20]. In such wounds there is an interruption of tissue continuity with destruction of all the epidermal cell layers and of mesenchymal tissue, including vascular elements. Initially, skin wounds are filled with blood and a fibrin(More)
BACKGROUND/AIM Ascorbic acid modulates tissue healing but the value of ascorbic acid supplementation during anastomotic healing remains unclear. We examined the role of ascorbic acid treatment in experimental intestinal resection. METHODS Male Wistar albino rats (n = 30) were divided into three groups: sham treatment (group 1), and daily ascorbic acid(More)
Introduction Familial Mediterranean fever (FMF) is an autoinflammatory disorder characterized by recurrent, inflammatory, self-limited episodes of fever and serositis. Neutrophils are one of the key players in the pathophysiology of FMF. Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine involved in several inflammatory processes(More)
Methods Forty FMF patients and eighteen healthy controls with no known cardiovascular risk factors were included. All patients were receiving regular colchicine treatment and examinations were performed during attack-free periods. Serum samples were used for the determination of high sensitive C-reactive protein (hs-CRP), tissue factor (TF), tissue(More)
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