DAVID SARPHIE

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High-velocity powder injection is a promising new drug-delivery technique that provides needle- and pain-free delivery of traditional drugs, drugs from biotechnology such as proteins, peptides, and oligonucleotides as well as traditional and genetic vaccines. The energy of a transient helium gas jet accelerates fine drug particles of 20 microns-100 microns(More)
The PowderJect system, a device that uses compressed helium gas to accelerate microscopic particles into the skin, was used as a delivery system for DNA vaccines to elicit a virus-specific cytotoxic T cell response (CTL) in mice. Transient expression of beta-galactosidase (beta-Gal) was observed in the epidermis when gold particles coated with beta-Gal(More)
“ Students here are basically apat­ hetic," Dean o f Students James Roemer commented to a less than capacity crowd at last n igh t’s security seminar in LaFortune Stu­ dent Center. Eight students were in attendance. The seminar was jo in tly con­ ducted by Roemer, Assistant D irec­ to r o f Security Rex Rakow, and investigator Ann Schelllnger. It focused on(More)
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