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Oxytocin pathway gene networks in the human brain
Oxytocin is a neuropeptide involved in animal and human reproductive and social behavior. Three oxytocin signaling genes have been frequently implicated in human social behavior: OXT (structural geneExpand
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Genetics of brain age suggest an overlap with common brain disorders
Numerous genetic and environmental factors contribute to psychiatric disorders and other brain disorders. Common risk factors likely converge on biological pathways regulating the optimization ofExpand
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The serotonin transporter gene polymorphism 5-HTTLPR moderates the effects of stress on attention-deficit/hyperactivity disorder.
INTRODUCTION The role of the serotonin transporter gene polymorphism 5-HTTLPR in attention-deficit/hyperactivity disorder (ADHD) is unclear. Heterogeneity of findings may be explained byExpand
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Common brain disorders are associated with heritable patterns of apparent aging of the brain
Common risk factors for psychiatric and other brain disorders are likely to converge on biological pathways influencing the development and maintenance of brain structure and function across life.Expand
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The interaction between 5-HTTLPR and stress exposure influences connectivity of the executive control and default mode brain networks
We recently reported that the serotonin transporter polymorphism 5-HTTLPR moderates the relation between stress exposure and attention-deficit/hyperactivity disorder (ADHD) severity. ThisExpand
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Voxel-based morphometry analysis reveals frontal brain differences in participants with ADHD and their unaffected siblings.
BACKGROUND Data on structural brain alterations in patients with attention-deficit/hyperactivity disorder (ADHD) have been inconsistent. Both ADHD and brain volumes have a strong genetic loading, butExpand
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Brain scans from 21297 individuals reveal the genetic architecture of hippocampal subfield volumes
The hippocampus is a heterogeneous structure, comprising histologically distinguishable subfields. These subfields are differentially involved in memory consolidation, spatial navigation and patternExpand
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Interplay between stress response genes associated with attention‐deficit hyperactivity disorder and brain volume
The glucocorticoid receptor plays a pivotal role in the brain's response to stress; a haplotype of functional polymorphisms in the NR3C1 gene encoding this receptor has been associated withExpand
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Population-based neuroimaging reveals traces of childbirth in the maternal brain
Pregnancy and childbirth involve maternal brain adaptations that promote attachment to and protection of the newborn. Using brain imaging and machine learning, we provide evidence for a positiveExpand
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Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk.
Importance Between-individual variability in brain structure is determined by gene-environment interactions, possibly reflecting differential sensitivity to environmental and genetic perturbations.Expand
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