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Melamine-contaminated powdered formula and urolithiasis in young children.
BACKGROUND A recent epidemic of melamine contamination of baby formula in China has been associated with the development of urinary tract stones, though the clinical manifestations and predisposing… Expand
Over-expression of hypoxia-inducible factor-1 alpha in vitro protects the cardiac fibroblasts from hypoxia-induced apoptosis
Objectives A great number of studies indicate that cardiac fibroblasts are essential for maintaining the structure and function of heart. Hypoxia-inducible factor-1 alpha (HIF-1&agr;) is a central… Expand
Genetic polymorphism in chemokine CCL22 and susceptibility to Helicobacter pylori infection‐related gastric carcinoma
Gastric carcinoma is widely considered to be related to Helicobacter pylori infection, and the chemokine (C‐C motif) ligand 22 (CCL22) plays an important role in suppressing immune responses against… Expand
Association of TGF-β1 gene polymorphisms in exon1 and blood levels with essential hypertension
Abstract Aims. Based on a case–control study, we investigated the relationship between +869T/C and +915G/C gene polymorphisms in transforming growth factor-β1 (TGF-β1), protein levels and essential… Expand
Peripheral CD4+ T cell subsets and antibody response in COVID-19 convalescent individuals.
- Fang Gong, Yaping Dai, +8 authors Pengcheng Zhou
- The Journal of clinical investigation
- 25 August 2020
BACKGROUND Marked progress is achieved in understanding the physiopathology of COVID-19 that caused global pandemics. However, CD4+ T cell population that is critical for antibody response in… Expand
AtRTP5 negatively regulates plant resistance to Phytophthora pathogens by modulating the biosynthesis of endogenous jasmonic acid and salicylic acid
Summary Plants have evolved powerful immune systems to recognize pathogens and avoid invasions, but the genetic basis of plant susceptibility is less well‐studied, especially to oomycetes, which… Expand
Cytomegalovirus- and Epstein-Barr Virus-Induced T-Cell Expansions in Young Children Do Not Impair Naive T-cell Populations or Vaccination Responses: The Generation R Study.
- D. van den Heuvel, M. Jansen, +10 authors M. V. van Zelm
- The Journal of infectious diseases
- 15 January 2016
BACKGROUND Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) induce effector memory T-cell expansions, which are variable and potentially depend on the age at primary exposure and coinfections. We… Expand
SIRT1 and FOXO Mediate Contractile Differentiation of Vascular Smooth Muscle Cells under Cyclic Stretch
- K. Huang, Z. Yan, +7 authors Z. Jiang
- Biology, Medicine
- Cellular Physiology and Biochemistry
- 1 November 2015
Background/Aims: Physiological mechanical stretch in vivo helps to maintain the quiescent contractile differentiation of vascular smooth muscle cells (VSMCs), but the underlying mechanisms are still… Expand
Quantitative Proteomics Reveals the Essential Roles of Stromal Interaction Molecule 1 (STIM1) in the Testicular Cord Formation in Mouse Testis*
Testicular cord formation in male gonadogenesis involves assembly of several cell types, the precise molecular mechanism is still not well known. With the high-throughput quantitative proteomics… Expand
Expression and clinical significance of aminopeptidase N/CD13 in non-small cell lung cancer.
- Q. Zhang, J. Wang, Hai-qing Zhang, D. Zhao, Z. Zhang, S. Zhang
- Journal of cancer research and therapeutics
BACKGROUND The objective of this study was to analyze the expression of aminopeptidase N/CD13 (APN/CD13) in non-small cell lung cancer (NSCLC) and investigate its correlation with various clinical… Expand